143-07-7

DATA ITEMS CITED :

11

MOLECULAR FORMULA :

C12-H24-O2

MOLECULAR WEIGHT :

200.36

WISWESSER LINE NOTATION :

QV11

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - rabbit

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

12 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

131 mg/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

333 gm/kg/13W-C

TOXIC EFFECTS :

Behavioral - food intake (animal) Behavioral - fluid intake

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

108 gm/kg/15W-I

TOXIC EFFECTS :

Tumorigenic - neoplastic by RTECS criteria Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :

Cytogenetic analysis

TEST SYSTEM :

Yeast - Saccharomyces cerevisiae

DOSE/DURATION :

10 mg/L

REFERENCE :

NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 294,263,1981 *** REVIEWS *** TOXICOLOGY REVIEW AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 21,100,1960 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84696 No. of Facilities: 1256 (estimated) No. of Industries: 14 No. of Occupations: 34 No. of Employees: 14960 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84696 No. of Facilities: 4690 (estimated) No. of Industries: 51 No. of Occupations: 50 No. of Employees: 77970 (estimated) No. of Female Employees: 17300 (estimated)