159736-35-3

159736-35-3 structure

Name: Wikstrol A
Chemical Name: 3',5,5',7,7'-Pentahydroxy-2,2'-bis(4-hydroxyphenyl)-3',4'-dihydro-2'H,4H-3,8'-bichromen-4-one
CAS Number: 159736-35-3
Molecular Formula: C₃₀H₂₂O₁₀
Molecular Weight: 542.490
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2018-07-21 23:16:01
Modify Date: 2024-01-18 16:54:56
Wikstrol A is a potent antifungal, antimitotic and anti-HIV-1 Agent. Wikstrol A induces morphological deformation of P. oryzae mycelia with an MMDC value of 70.1 µM. Wikstrol A shows activity against microtubule polymerization with an IC50 value of 131 µM. Wikstrol A shows anti-HIV-1 activity with an IC50 value of 67.8 µM[1].

Name	3',5,5',7,7'-Pentahydroxy-2,2'-bis(4-hydroxyphenyl)-3',4'-dihydro-2'H,4H-3,8'-bichromen-4-one
Synonyms	[3,8'-Bi-4H-1-benzopyran]-4-one, 2',3'-dihydro-3',5,5',7,7'-pentahydroxy-2,2'-bis(4-hydroxyphenyl)- 3',5,5',7,7'-Pentahydroxy-2,2'-bis(4-hydroxyphenyl)-3',4'-dihydro-2'H,4H-3,8'-bichromen-4-one

Description	Wikstrol A is a potent antifungal, antimitotic and anti-HIV-1 Agent. Wikstrol A induces morphological deformation of P. oryzae mycelia with an MMDC value of 70.1 µM. Wikstrol A shows activity against microtubule polymerization with an IC50 value of 131 µM. Wikstrol A shows anti-HIV-1 activity with an IC50 value of 67.8 µM[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
Target	HIV-1:67.8 (IC50)
References	[1]. Hu K, et al. Antifungal, antimitotic and anti-HIV-1 agents from the roots of Wikstroemia indica. Planta Med. 2000 Aug;66(6):564-7.