Name | Atreleuton |
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Synonyms | COX/5-LO-IN-1 |
Description | COX/5-LO-IN-1 is an inhibitor of cylooxygenase and 5-lipoxygenase, used for the research of inflammatory and allergic disease states. |
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Related Catalog | |
Target |
5-Lipoxygenase:2 μM (IC50) COX |
In Vitro | COX/5-LO-IN-1 reduces the biosynthesis of leukotrienes B4, C4, D4, and E4 and cyclooxygenase products such as prostaglandins and thromboxane and are useful in the treatment of inflammatory and allergic disease states[1]. COX/5-LO-IN-1 shows inhibitory activities against 5-lipoxygenase, with IC50 of 0.2 μM in human whole blood[2]. |
References |
[1]. Lipoxygenase and cyclooxygenase inhibiting compounds. US 5516789 A |
Molecular Formula | C16H15FN2O2S |
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Molecular Weight | 318.371 |