1262858-14-9

1262858-14-9 structure

1262858-14-9 structure

Name: BACE-1 inhibitor 1
Chemical Name: BACE-1 inhibitor 1
CAS Number: 1262858-14-9
Molecular Formula: C₁₇H₁₄BrF₃N₄O₂
Molecular Weight: 443.22
Catalog: Signaling Pathways Neuronal Signaling Beta-secretase
Create Date: 2019-03-30 15:03:34
Modify Date: 2024-01-07 10:52:37
BACE-1 inhibitor 1 (Compound 8a) is a potent BACE-1 inhibitor with an IC50 of 56 nM[1].

Name	BACE-1 inhibitor 1

Description	BACE-1 inhibitor 1 (Compound 8a) is a potent BACE-1 inhibitor with an IC50 of 56 nM[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Beta-secretase Research Areas >> Neurological Disease
Target	IC50: 56 nM (BACE-1)[1]
References	[1]. Veenstra SJ, et al. Discovery of amino-1,4-oxazines as potent BACE-1 inhibitors. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2195-2200.

Molecular Formula	C₁₇H₁₄BrF₃N₄O₂
Molecular Weight	443.22