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1679330-37-0

1679330-37-0 structure
1679330-37-0 structure
  • Name: AZ Dyrk1B 33
  • Chemical Name: AZ-Dyrk1B-33
  • CAS Number: 1679330-37-0
  • Molecular Formula: C19H16N4
  • Molecular Weight: 300.36
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK DYRK
  • Create Date: 2020-06-04 08:32:03
  • Modify Date: 2024-01-10 13:20:37
  • AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor, with an IC50 of 7 nM[1].
Name AZ-Dyrk1B-33
Description AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor, with an IC50 of 7 nM[1].
Related Catalog
Target

IC50: 7 nM (Dyrk1B)[1]

In Vitro AZ-Dyrk1B-33 shows inhibition of phosphorylation of Dyrk pS421 in cells with an IC50 of 0.192 μM[1]. AZ-Dyrk1B-33 shows no effect in sensitization[1].
References

[1]. Kettle JG, et al. Discovery and optimization of a novel series of Dyrk1B kinase inhibitors to explore a MEK resistance hypothesis. J Med Chem. 2015 Mar 26;58(6):2834-44.
Molecular Formula C19H16N4
Molecular Weight 300.36

Chemsrc provides CAS#:1679330-37-0 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 1679330-37-0 | Chemsrc address: https://www.chemsrc.com/en/baike/1565054.html

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