2641838-98-2

2641838-98-2 structure

Name: Thalidomide-NH-PEG7
Chemical Name: Thalidomide-NH-PEG7
CAS Number: 2641838-98-2
Molecular Formula: C₂₇H₃₉N₃O₁₁
Molecular Weight: 581.61
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2021-09-14 11:31:58
Modify Date: 2024-01-11 11:58:33
Thalidomide-NH-PEG7 is a synthesized E3 ligase ligand-linker conjugate for ADC. Thalidomide-NH-PEG7 can be connected to the ligand for protein by a linker to form PROTAC iRucaparib-AP6, a highly specific PARP1 degrader[1].

Name	Thalidomide-NH-PEG7

Description	Thalidomide-NH-PEG7 is a synthesized E3 ligase ligand-linker conjugate for ADC. Thalidomide-NH-PEG7 can be connected to the ligand for protein by a linker to form PROTAC iRucaparib-AP6, a highly specific PARP1 degrader[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	Cereblon
References	[1]. Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation.Nat Chem Biol. 2019 Dec;15(12):1223-1231.

Molecular Formula	C₂₇H₃₉N₃O₁₁
Molecular Weight	581.61

Hazard Codes	Xi