1965342-41-9

1965342-41-9 structure

1965342-41-9 structure

Name: ODN 105871
Chemical Name: ODN 105871
CAS Number: 1965342-41-9
Molecular Formula:
Molecular Weight:
Catalog: Signaling Pathways Immunology/Inflammation Toll-like Receptor (TLR)
Create Date: 2023-01-25 18:40:16
Modify Date: 2024-04-02 19:51:28
ODN 105871, a G-modified inhibitory oligonucleotide (INH-ODN), is a selective TLR7 inhibitor. ODN 105871 can be uesd for inflammatory immune responses research[1].

Name	ODN 105871

Description	ODN 105871, a G-modified inhibitory oligonucleotide (INH-ODN), is a selective TLR7 inhibitor. ODN 105871 can be uesd for inflammatory immune responses research[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Inflammation/Immunology
In Vitro	ODN 105871 potently inhibits the TLR7-induced TNF-α response in bone marrow-derived macrophages (BMDMs)[1]. In case of Imiquimod-stimulated B cells, ODN 105871 reduces the ATP content to the pretreatment level[1].
References	[1]. Franziska Römmler, et al. Guanine modification of inhibitory oligonucleotides potentiates their suppressive function. J Immunol. 2013 Sep 15;191(6):3240-53.

No Any Chemical & Physical Properties