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702701-70-0

702701-70-0 structure
702701-70-0 structure
  • Name: Benzyl-PEG3-MS
  • Chemical Name: methanesulfonic acid 2-[2-(2-benzyloxy-ethoxy)-ethoxy]-ethyl ester
  • CAS Number: 702701-70-0
  • Molecular Formula: C14H22O6S
  • Molecular Weight: 318.38600
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-06-14 06:16:33
  • Modify Date: 2024-01-03 11:51:20
  • Benzyl-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name methanesulfonic acid 2-[2-(2-benzyloxy-ethoxy)-ethoxy]-ethyl ester
Synonyms (2-{2-[2-(benzyloxy)ethoxy]ethoxy}ethyl) methanesulfonate
triethylene glycol benzyl mesyl ether
Description Benzyl-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C14H22O6S
Molecular Weight 318.38600
Exact Mass 318.11400
PSA 79.44000
LogP 2.29340
Precursor  0

DownStream  1