606130-90-9
606130-90-9 structure
- Name: m-PEG4-azide
- Chemical Name: 1-azido-2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethane
- CAS Number: 606130-90-9
- Molecular Formula: C9H19N3O4
- Molecular Weight: 233.26500
- Catalog: Chemical reagent Organic reagent Azide
- Create Date: 2018-12-26 12:51:56
- Modify Date: 2024-01-01 18:08:40
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m-PEG4-azide (13-Azido-2,5,8,11-tetraoxatridecane) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
| Name | 1-azido-2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethane |
|---|---|
| Synonyms |
AmbotzPEG1690
Me(OCH2CH2)4N3 O-(2-Azidoethyl)-O inverted exclamation marka-methyl-triethylene glycol MeO-PEG4-Azide 1-azido-11-methoxy-3,6,9-trioxaundecane 1-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-2-methoxyethane m-dPEG.(TM).4-azide 13-Azido-2,5,8,11-tetraoxatridecane |
| Description | m-PEG4-azide (13-Azido-2,5,8,11-tetraoxatridecane) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C9H19N3O4 |
|---|---|
| Molecular Weight | 233.26500 |
| Exact Mass | 233.13800 |
| PSA | 86.67000 |
| LogP | 0.44566 |
| Index of Refraction | 1.4500 to 1.4540 |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn |
| Risk Phrases | 22 |
| RIDADR | NONH for all modes of transport |
| HS Code | 29299090 |
|
~%
606130-90-9 |
| Literature: Li, Guangtao; Bhosale, Sheshanath V.; Wang, Tianyu; Hackbarth, Steffen; Roeder, Beate; Siggel, Ulrich; Fuhrhop, Juergen-Hinrich Journal of the American Chemical Society, 2003 , vol. 125, # 35 p. 10693 - 10702 |
|
~97%
606130-90-9 |
| Literature: Kitto, Heather J.; Schwartz, Erik; Nijemeisland, Marlies; Koepf, Matthieu; Cornelissen, Jeroen J. L. M.; Rowan, Alan E.; Nolte, Roeland J. M. Journal of Materials Chemistry, 2008 , vol. 18, # 46 p. 5615 - 5624 |
| Precursor 2 | |
|---|---|
| DownStream 1 | |
