83824-29-7
83824-29-7 structure
- Name: CH2COOH-PEG6-CH2COOH
- Chemical Name: 2-[2-[2-[2-[2-[2-[2-(carboxymethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
- CAS Number: 83824-29-7
- Molecular Formula: C16H30O11
- Molecular Weight: 398.40300
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-21 20:59:39
- Modify Date: 2024-01-10 13:02:41
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CH2COOH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-[2-[2-[2-[2-[2-[2-(carboxymethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid |
|---|---|
| Synonyms |
3,6,9,12,15,18,21-Heptaoxatricosanedioic acid
3,6,9,12,15,18,21-heptaoxatricosane-1,23-dioic acid |
| Description | CH2COOH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C16H30O11 |
|---|---|
| Molecular Weight | 398.40300 |
| Exact Mass | 398.17900 |
| PSA | 139.21000 |
| Hazard Codes | Xi |
|---|
|
~97%
83824-29-7 |
| Literature: Wittmann, Valentin; Takayama, Shuichi; Gong, Ke Wei; Weitz-Schmidt, Gabriele; Wong, Chi-Huey Journal of Organic Chemistry, 1998 , vol. 63, # 15 p. 5137 - 5143 |
|
~%
83824-29-7 |
| Literature: Wittmann, Valentin; Takayama, Shuichi; Gong, Ke Wei; Weitz-Schmidt, Gabriele; Wong, Chi-Huey Journal of Organic Chemistry, 1998 , vol. 63, # 15 p. 5137 - 5143 |
| Precursor 1 | |
|---|---|
| DownStream 1 | |
