HO-PEG6-CH2COOH

Modify Date: 2024-01-15 11:27:05

HO-PEG6-CH2COOH Structure
HO-PEG6-CH2COOH structure
Common Name HO-PEG6-CH2COOH
CAS Number 120394-66-3 Molecular Weight 340.37
Density N/A Boiling Point N/A
Molecular Formula C14H28O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HO-PEG6-CH2COOH


HO-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name HO-PEG6-CH2COOH

 HO-PEG6-CH2COOH Biological Activity

Description HO-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H28O9
Molecular Weight 340.37