CM 764
Modify Date: 2024-01-18 11:09:07
CM 764 structure
|
Common Name | CM 764 | ||
|---|---|---|---|---|
| CAS Number | 1350296-29-5 | Molecular Weight | 426.492 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H27FN4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CM 764A potent, selective sigma-2 receptor agonist with Ki of 3.5 nM, 25-fold selectivity over sigma-1 receptors (Ki=86.6 nM); increases reduction of MTT in human SK-N-SH neuroblastoma, produces an immediate, robust, and transient increase in cytosolic calcium, consistent with sigma-2 receptor activation; increases total NAD(+)/NADH level, the ATP level, HIF1α and VEGF levelsin SK-N-SH cells. |
| Name | CM 764 |
|---|
| Description | A potent, selective sigma-2 receptor agonist with Ki of 3.5 nM, 25-fold selectivity over sigma-1 receptors (Ki=86.6 nM); increases reduction of MTT in human SK-N-SH neuroblastoma, produces an immediate, robust, and transient increase in cytosolic calcium, consistent with sigma-2 receptor activation; increases total NAD(+)/NADH level, the ATP level, HIF1α and VEGF levelsin SK-N-SH cells. |
|---|---|
| References | References 1. Nicholson H, et al. J Pharmacol Exp Ther. 2016 Feb;356(2):232-43. View Related Products by Target Sigma Receptor |
| Molecular Formula | C23H27FN4O3 |
|---|---|
| Molecular Weight | 426.492 |