PBRM1-BD2-IN-8

Modify Date: 2024-04-12 18:52:33

PBRM1-BD2-IN-8 structure	Common Name	PBRM1-BD2-IN-8
	CAS Number	2819989-75-6	Molecular Weight	317.18
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₃BrN₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PBRM1-BD2-IN-8

PBRM1-BD2-IN-8 (compound 34) is a potent PBRM1 Bromodomain inhibitor (PBRM1-BD2 Kd=4.4 μM, PBRM1-BD2 IC50=0.16 μM; PBRM1-BD5 Kd=25 μM). PBRM1-BD2-IN-8 shows anti-cancer activity[1].

Name	PBRM1-BD2-IN-8

Description	PBRM1-BD2-IN-8 (compound 34) is a potent PBRM1 Bromodomain inhibitor (PBRM1-BD2 Kd=4.4 μM, PBRM1-BD2 IC50=0.16 μM; PBRM1-BD5 Kd=25 μM). PBRM1-BD2-IN-8 shows anti-cancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Target	IC50: 0.16 μM (PBRM1-BD2)[1]
In Vitro	PBRM1-BD2-IN-8 (0-100 μM; 48 h) inhibits the growth of PBRM1-dependent prostate cancer cells[1]. Cell Viability Assay[1] Cell Line: LNCaP cells Concentration: 0-100 μM Incubation Time: 48 hours Result: Inhibited the growth of LNCaP cells with IC50 value of about 9 μM.

Molecular Formula	C₁₅H₁₃BrN₂O
Molecular Weight	317.18

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PBRM1-BD2-IN-8
Price: Click To Check
Purity: 99.48%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

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