Werner syndrome RecQ helicase-IN-2

Modify Date: 2024-04-06 19:08:17

Werner syndrome RecQ helicase-IN-2 Structure
Werner syndrome RecQ helicase-IN-2 structure
Common Name Werner syndrome RecQ helicase-IN-2
CAS Number 2869954-51-6 Molecular Weight 681.66
Density N/A Boiling Point N/A
Molecular Formula C32H34F3N9O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Werner syndrome RecQ helicase-IN-2


Werner syndrome RecQ helicase-IN-2 (example 57) is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor and can be used in cancer research[1].

 Names

Name Werner syndrome RecQ helicase-IN-2

 Werner syndrome RecQ helicase-IN-2 Biological Activity

Description Werner syndrome RecQ helicase-IN-2 (example 57) is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor and can be used in cancer research[1].
Related Catalog
In Vitro Werner syndrome RecQ helicase-IN-2 (example 57)作用于 WRN ATPase 的IC50 值为100 nM,作用于 SW48和 DLD1 WRN-KO 细胞系的GI50 值分别是100 nM和大于10 μM[1]。
References

[1]. Triazolo-pyrimidine analogues for treating diseases connected to the inhibiton of werner syndrome recq helicase (wrn). WO2022249060

 Chemical & Physical Properties

Molecular Formula C32H34F3N9O5
Molecular Weight 681.66