Azide-PEG8-alcohol

Modify Date: 2024-01-09 15:38:27

Azide-PEG8-alcohol Structure
Azide-PEG8-alcohol structure
Common Name Azide-PEG8-alcohol
CAS Number 352439-36-2 Molecular Weight 395.44900
Density N/A Boiling Point N/A
Molecular Formula C16H33N3O8 Melting Point N/A
MSDS USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of Azide-PEG8-alcohol


Azide-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Synonym More Synonyms

 Azide-PEG8-alcohol Biological Activity

Description Azide-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C16H33N3O8
Molecular Weight 395.44900
Exact Mass 395.22700
PSA 134.59000
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26
RIDADR NONH for all modes of transport
HS Code 2929909090

 Customs

HS Code 2929909090
Summary 2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

1-azido-23-hydroxy-3,6,9,12,15,18,21-heptaoxatricosane
AmbotzPEG1088
Azido-PEG (n=7)
23-azido-3,6,9,12,15,18,21-heptaoxatricosan-1-ol
O-(2-azidoethyl)heptaethyleneglycol
3,6,9,12,15,18,21-Heptaoxatricosan-1-ol,23-azido
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