Tetraethylene Glycol Monobenzyl Ether

Modify Date: 2024-01-11 19:40:41

Tetraethylene Glycol Monobenzyl Ether structure	Common Name	Tetraethylene Glycol Monobenzyl Ether
	CAS Number	86259-87-2	Molecular Weight	284.348
	Density	1.1±0.1 g/cm3	Boiling Point	398.7±32.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₂₄O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	194.9±25.1 °C

Use of Tetraethylene Glycol Monobenzyl Ether

BnO-PEG4-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name	Tetraethylene Glycol Monobenzyl Ether
Synonym	More Synonyms

Description	BnO-PEG4-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog	Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Andrew P. Crew, et al. Tau-protein targeting protacs and associated methods of use. Patent. US20180125821A1.

Density	1.1±0.1 g/cm3
Boiling Point	398.7±32.0 °C at 760 mmHg
Molecular Formula	C₁₅H₂₄O₅
Molecular Weight	284.348
Flash Point	194.9±25.1 °C
Exact Mass	284.162384
PSA	57.15000
LogP	0.18
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.500

Tetraethylene Glycol Monobenzyl Ether MSDS(Chinese)

HS Code	2909499000

2,2'-((Oxybis(e...

CAS#:112-60-7

Benzyl bromide

CAS#:100-39-0

~94%

Tetraethylene G...

CAS#:86259-87-2

Literature: WO2008/54466 A2, ; Page/Page column 32-33 ;

2,2'-((Oxybis(e...

CAS#:112-60-7

Benzyl chloride

CAS#:100-44-7

~85%

Tetraethylene G...

CAS#:86259-87-2

Literature: Synthetic Communications, , vol. 20, # 6 p. 799 - 807

Benzyl bromide

CAS#:100-39-0

~89%

Tetraethylene G...

CAS#:86259-87-2

Literature: WO2007/112100 A2, ; Page/Page column 44; 103; 110; 128; 130; 138 ;

2,2'-((Oxybis(e...

CAS#:112-60-7

Benzyl chloride

CAS#:100-44-7

2-{2-[2-(Benzyl...

CAS#:55489-58-2

Tetraethylene G...

CAS#:86259-87-2

Literature: Angewandte Chemie - International Edition, , vol. 48, # 7 p. 1248 - 1252

ETHYLENE OXIDE

CAS#:75-21-8

Benzyl alcohol

CAS#:100-51-6

~38%

Diethylene Glyc...

CAS#:2050-25-1

2-(Benzyloxy)ethanol

CAS#:622-08-2

Detail

Literature: ACH - Models in Chemistry, , vol. 134, # 2-3 p. 241 - 252

2-(Benzyloxy)ethanol

CAS#:622-08-2

Tetraethylene G...

CAS#:86259-87-2

Literature: ACH - Models in Chemistry, , vol. 134, # 2-3 p. 241 - 252

Benzyl chloride

CAS#:100-44-7

Tetraethylene G...

CAS#:86259-87-2

Literature: ACH - Models in Chemistry, , vol. 133, # 1-2 p. 21 - 26

Benzyl alcohol

CAS#:100-51-6

Tetraethylene G...

CAS#:86259-87-2

Literature: ACH - Models in Chemistry, , vol. 134, # 2-3 p. 241 - 252

ETHYLENE OXIDE

CAS#:75-21-8

Benzyl alcohol

CAS#:100-51-6

Diethylene Glyc...

CAS#:2050-25-1

2-(Benzyloxy)ethanol

CAS#:622-08-2

Detail

Literature: Tetrahedron Letters, , vol. 38, # 4 p. 661 - 664

Precursor 6
CAS#:112-60-7 2,2'-((Oxybis(e... CAS#:100-39-0 Benzyl bromide CAS#:100-44-7 Benzyl chloride CAS#:75-21-8 ETHYLENE OXIDE
CAS#:100-51-6 Benzyl alcohol CAS#:622-08-2 2-(Benzyloxy)ethanol
DownStream 10
CAS#:105891-51-8 2-[2-[2-(2-chlo... CAS#:57671-28-0 BnO-PEG5-OH CAS#:5117-19-1 3,6,9,12,15,18,... CAS#:3386-18-3 nonaethylene glycol
CAS#:86770-74-3 Amino-PEG4-alcohol CAS#:5617-32-3 heptaethylene glycol CAS#:36366-93-5 2-[2-[2-(2-phen... CAS#:6790-09-6 PEG13
CAS#:23783-42-8 Tetraethylene g... CAS#:105891-55-2 2-[2-[2-[2-[2-[...

HS Code	2909499000
Summary	2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%