SNIPER(ABL)-033

Modify Date: 2024-01-21 19:42:12

SNIPER(ABL)-033 structure	Common Name	SNIPER(ABL)-033
	CAS Number	2222354-18-7	Molecular Weight	1211.42
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆₁H₇₃F₃N₁₀O₉S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SNIPER(ABL)-033

SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 0.3 μM[1].

Name	SNIPER(ABL)-033

Description	SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 0.3 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Bcr-Abl
References	[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

Molecular Formula	C₆₁H₇₃F₃N₁₀O₉S₂
Molecular Weight	1211.42