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6-糠氨基嘌呤

6-糠氨基嘌呤用途

Kinetin (N6-furfuryladenine)是一种参与细胞分裂的植物生长激素。

6-糠氨基嘌呤名称

[ CAS 号 ]:
525-79-1

[ 中文名 ]:
糖氨基嘌呤

[ 英文名 ]:
6-(Furfurylamino)purine

[中文别名 ]:

[英文别名 ]:

6-Furfurylaminopurine,N6-Furfuryladenine
N-(2-Furylmethyl)-7H-purin-6-amine
N-furfuryl-7H-purin-6-amine
N-(2-Furylmethyl)-3H-purin-6-amine
N-(Furan-2-ylmethyl)-1H-purin-6-amine
MFCD00075757
7H-Purin-6-amine, N-(2-furanylmethyl)-
T56 BM DN FN HNJ IM1- BT5OJ
cytokinin
fap

6-糠氨基嘌呤生物活性

[ 描述 ]:

Kinetin (N6-furfuryladenine)是一种参与细胞分裂的植物生长激素。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

天然产物 >> 生物碱

研究领域 >> 神经疾病

[参考文献]

[1]. Kunikowska A, et al. Kinetin induces cell death in root cortex cells of Vicia faba ssp. minor seedlings. Protoplasma. 2013 Aug;250(4):851-61.

[2]. Axelrod FB, et al. Kinetin improves IKBKAP mRNA splicing in patients with familial dysautonomia. Pediatr Res. 2011 Nov;70(5):480-3.

[3]. Hims MM, et al. Therapeutic potential and mechanism of kinetin as a treatment for the human splicing disease familial dysautonomia. J Mol Med (Berl). 2007 Feb;85(2):149-61.

[4]. Griffaut B, et al. Cytotoxic effects of kinetin riboside on mouse, human and plant tumour cells. Int J Biol Macromol. 2004 Aug;34(4):271-5.

[相关活性小分子]

6-糠氨基嘌呤物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
367.6±52.0 °C at 760 mmHg

[ 熔点 ]:
269-271 °C (dec.)(lit.)

[ 分子式 ]:
C₁₀H₉N₅O

[ 分子量 ]:
215.211

[ 闪点 ]:
176.1±30.7 °C

[ 精确质量 ]:
215.080704

[ PSA ]:
79.63000

[ LogP ]:
-0.56

[ 外观性状 ]:
灰白色非晶形的粉末

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.774

[ 储存条件 ]:
−20°C

[ 水溶解性 ]:
H2O: soluble

6-糠氨基嘌呤MSDS

详细MSDS(安全技术说明书)

6-糠氨基嘌呤毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU6270000

CHEMICAL NAME :: Adenine, N-furfuryl-

CAS REGISTRY NUMBER :: 525-79-1

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C10-H9-N5-O

MOLECULAR WEIGHT :: 215.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Human Leukocyte

DOSE/DURATION :: 100 umol/L

REFERENCE :: EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 32,29,1976 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

6-糠氨基嘌呤安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
68-36/37/38

[ 安全声明 (欧洲) ]:
S23-S24/25-S22

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
AU6270000

[ 海关编码 ]:
29349990

6-糠氨基嘌呤合成路线

详细合成路线

6-糠氨基嘌呤上下游产品

6-糠氨基嘌呤上游产品

6-糠氨基嘌呤下游产品

6-糠氨基嘌呤制备

暂无

6-糠氨基嘌呤海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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