3738-70-3

3738-70-3结构式

常用中文名：盐酸吐根酚碱
常用英文名：Cephaeline dihydrochloride
CAS号：3738-70-3
分子式：C₂₈H₄₀Cl₂N₂O₄
分子量：539.534
相关类别：原料药消化系统用药止吐催吐药
发布时间：2018-04-09 08:00:00
更新时间：2024-01-06 21:11:21
盐酸头孢菌素((-)-盐酸头孢菌素)是印度吐根中的一种酚性生物碱。盐酸头孢喹对寨卡病毒(ZIKV)和埃博拉病毒(EBOV)感染均具有有效的抑制作用[1][2]。

中文名	盐酸吐根酚碱
英文名	cephaeline hydrochloride
中文别名	吐根酚碱盐酸盐(七水)
英文别名	10,11,7'-Trimethoxy-emetan-6'-ol,Hydrochlorid AC1NUT82 CHEBI:2535 (2R,3R,11bS)-(+)-2-(3,4-dihydro-6-hydroxy-7-methoxy-1-isoquinolyl)methyl-3-ethyl-1,3,4,6,7,11b-hexahydro-8-hydroxy-9,10-dimethoxy-2H-benzo[a]quinolizine (alangicine) Alangicine 7',10,11-Trimethoxyemetan-6'-ol dihydrochloride 2-(6-hydroxy-7-methoxy-3,4-dihydro-isoquinolin-1-ylmethyl)-3-ethyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-8-ol Cephaeline dihydrochloride 10,11,7'-trimethoxy-emet-1'-ene-9,6'-diol Emetan-6'-ol, 7',10,11-trimethoxy-, dihydrochloride (9CI) 10,11,7'-trimethoxy-emetan-6'-ol,dihydrochloride (2R,3R,11bS)-3-ethyl-2-(6-hydroxy-7-methoxy-3,4-dihydroisoquinolin-1-ylmethyl)-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-8-ol 6-Isoquinolinol, 1-[[(2S,3R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-, (1R)-, hydrochloride (1:2) 10,11,7'-Trimethoxy-emetan-6'-ol,Dihydrochlorid Emetan-6'-ol, 7',10,11-trimethoxy-, dihydrochloride

描述	盐酸头孢菌素((-)-盐酸头孢菌素)是印度吐根中的一种酚性生物碱。盐酸头孢喹对寨卡病毒(ZIKV)和埃博拉病毒(EBOV)感染均具有有效的抑制作用[1][2]。
相关类别	信号通路 >> 抗感染 >> 流感病毒研究领域 >> 感染信号通路 >> 抗感染 >> 丝状病毒
参考文献	[1]. N.P.Sahu, et al. Determination of emetine and cephaeline in Ipecac roots by high- performance liquid chromatography. Journal of Chromatography A. 1982 Apr; 238( 2):525-529. [2]. Yang S, et al. Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry. Cell Discov. 2018 Jun 5;4:31.