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2641054-60-4

2641054-60-4 structure
2641054-60-4 structure
  • Name: LRRK2-IN-3
  • Chemical Name: LRRK2-IN-3
  • CAS Number: 2641054-60-4
  • Molecular Formula: C25H29ClF2N6O2
  • Molecular Weight: 518.99
  • Catalog: Signaling Pathways Autophagy LRRK2
  • Create Date: 2022-04-07 15:07:15
  • Modify Date: 2024-01-11 08:18:06
  • LRRK2-IN-3 (compoubd 24) is a potent, selective, orally active and brain-penetrant inhibitor LRRK2, with IC50 of 2.6 nM in human PBMCs. LRRK2-IN-3 can be used for the research of Parkinson's disease[1].

Name LRRK2-IN-3
Description LRRK2-IN-3 (compoubd 24) is a potent, selective, orally active and brain-penetrant inhibitor LRRK2, with IC50 of 2.6 nM in human PBMCs. LRRK2-IN-3 can be used for the research of Parkinson's disease[1].
Related Catalog
Target

IC50: 2.6 nM (hPBMCs LRRK2)[1]

References

[1]. Keylor MH, et, al. Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors. J Med Chem. 2022 Jan 13;65(1):838-856.

Molecular Formula C25H29ClF2N6O2
Molecular Weight 518.99