2770269-44-6

2770269-44-6 structure
2770269-44-6 structure
  • Name: LRRK2-IN-8
  • Chemical Name: LRRK2-IN-8
  • CAS Number: 2770269-44-6
  • Molecular Formula: C16H12F2N6
  • Molecular Weight: 326.30
  • Catalog: Signaling Pathways Autophagy LRRK2
  • Create Date: 2023-04-03 10:38:10
  • Modify Date: 2024-04-02 15:27:33
  • LRRK2-IN-8 is a LRRK2 inhibitor. LRRK2-IN-8 inhibits LRRK2 (wt) and LRRK2 (G2019) with IC50s lower than 10 nM, and inhibits TYK2 and NUAK1 with IC50s of 10-100 nM[1].

Name LRRK2-IN-8
Description LRRK2-IN-8 is a LRRK2 inhibitor. LRRK2-IN-8 inhibits LRRK2 (wt) and LRRK2 (G2019) with IC50s lower than 10 nM, and inhibits TYK2 and NUAK1 with IC50s of 10-100 nM[1].
Related Catalog
Target

Tyk2:10-100 nM (IC50)

NUAK1:10-100 nM (IC50)

References

[1]. Jean TASSEL, et al. Kinase modulators and methods of use thereof. Patent. WO2022104206.

Molecular Formula C16H12F2N6
Molecular Weight 326.30