Name | LRRK2-IN-4 |
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Description | LRRK2-IN-4 is a potent, selective, CNS-penetran and orally active leucine-rich repeat kinase 2 (LRRK2) inhobitor with an IC50 of 2.6 nM. LRRK2-IN-4 has the potential for the research of Parkinson’s disease[1]. |
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Related Catalog | |
Target |
IC50: 2.6 nM (LRRK2)[1] |
In Vivo | LRRK2-IN-4 (compound 24) (p.o.) shows good oral bioavailability in male Wistar-Han rats (F=64%), male beagle dogs (F=65%)[1]. |
References |
Molecular Formula | C25H29ClF2N6O2 |
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Molecular Weight | 518.99 |