Amino-PEG3-CH2COOH

Modify Date: 2024-01-02 18:39:51

Amino-PEG3-CH2COOH Structure
Amino-PEG3-CH2COOH structure
Common Name Amino-PEG3-CH2COOH
CAS Number 134978-99-7 Molecular Weight 207.22400
Density N/A Boiling Point N/A
Molecular Formula C8H17NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amino-PEG3-CH2COOH


Amino-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]acetic acid
Synonym More Synonyms

 Amino-PEG3-CH2COOH Biological Activity

Description Amino-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C8H17NO5
Molecular Weight 207.22400
Exact Mass 207.11100
PSA 91.01000

 Synthetic Route

 Synonyms

2-<2-<2-(aminoethoxy)ethoxy>ethoxy>acetic acid
Acetic acid,[2-[2-(2-aminoethoxy)ethoxy]ethoxy]
11-amino-3,6,9-trioxaundecanoic acid
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