HS-PEG6-CH2CH2-Boc

Modify Date: 2024-01-02 11:06:59

HS-PEG6-CH2CH2-Boc Structure
HS-PEG6-CH2CH2-Boc structure
Common Name HS-PEG6-CH2CH2-Boc
CAS Number 1818294-40-4 Molecular Weight 426.565
Density 1.1±0.1 g/cm3 Boiling Point 488.8±45.0 °C at 760 mmHg
Molecular Formula C19H38O8S Melting Point N/A
MSDS N/A Flash Point 337.6±16.6 °C

 Use of HS-PEG6-CH2CH2-Boc


HS-PEG6-CH2CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Thiol-PEG6-t-butyl ester
Synonym More Synonyms

 HS-PEG6-CH2CH2-Boc Biological Activity

Description HS-PEG6-CH2CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 488.8±45.0 °C at 760 mmHg
Molecular Formula C19H38O8S
Molecular Weight 426.565
Flash Point 337.6±16.6 °C
Exact Mass 426.228729
LogP 0.32
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.466

 Safety Information

Hazard Codes Xi

 Synonyms

THIOL-PEG6-T-BUTYL ESTER
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