B-Raf IN 6

Modify Date: 2024-01-10 11:48:35

B-Raf IN 6 Structure
B-Raf IN 6 structure
Common Name B-Raf IN 6
CAS Number 2648698-34-2 Molecular Weight 546.59
Density N/A Boiling Point N/A
Molecular Formula C24H21F3N6O2S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of B-Raf IN 6


B-Raf IN 6 (compound 2c) is a potent inhibitor of protein kinase B-Raf with an IC50 of 1.7 nM. B-Raf IN 6 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease[1].

 Names

Name B-Raf IN 6

 B-Raf IN 6 Biological Activity

Description B-Raf IN 6 (compound 2c) is a potent inhibitor of protein kinase B-Raf with an IC50 of 1.7 nM. B-Raf IN 6 is devoid of binding to the secondary target PXR and resists rapid metabolism. B-Raf IN 6 has the potential for the research of cancer disease[1].
Related Catalog
References

[1]. Schneider M, et al. Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding. J Med Chem. 2022;65(2):1552-1566.

 Chemical & Physical Properties

Molecular Formula C24H21F3N6O2S2
Molecular Weight 546.59