B-Raf IN 11 structure
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Common Name | B-Raf IN 11 | ||
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CAS Number | 918504-27-5 | Molecular Weight | 458.27700 | |
Density | N/A | Boiling Point | 634.2°C | |
Molecular Formula | C17H14BrF2N3O3S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of B-Raf IN 11B-Raf IN 11 (ZINC72115182) is a selective B-RafV600E inhibitor (IC50=76 nM), shows selectivity for B-RafV600E over B-RafWT with selectivity of 3.1-fold. B-Raf IN 11 can be used in colorectal cancer research[1] |
Name | N-(3-(5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide |
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Synonym | More Synonyms |
Description | B-Raf IN 11 (ZINC72115182) is a selective B-RafV600E inhibitor (IC50=76 nM), shows selectivity for B-RafV600E over B-RafWT with selectivity of 3.1-fold. B-Raf IN 11 can be used in colorectal cancer research[1] |
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Related Catalog | |
Target |
B-RafV600E:76 nM (IC50) BRAFWT:238 nM (IC50) |
References |
Boiling Point | 634.2°C |
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Molecular Formula | C17H14BrF2N3O3S |
Molecular Weight | 458.27700 |
Exact Mass | 456.99100 |
PSA | 100.30000 |
LogP | 5.14010 |
Hazard Codes | Xi |
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HS Code | 2935009090 |
HS Code | 2935009090 |
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Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
N-[3-(5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide |