B-Raf IN 9

Modify Date: 2024-01-14 00:06:39

B-Raf IN 9 structure	Common Name	B-Raf IN 9
	CAS Number	2477725-18-9	Molecular Weight	400.50
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₀N₄OS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of B-Raf IN 9

B-Raf IN 9 (compound 8b) is a potent B-Raf inhibitor, with an IC50 of 24.79 nM. B-Raf IN 9 induces apoptosis and shows cell cycle arrest at G2/M phase. B-Raf IN 9 exhibits potent antitumor activity against human prostate cancer PC-3 cell line, with an IC50 of 7.83 µM[1].

Name	B-Raf IN 9

Description	B-Raf IN 9 (compound 8b) is a potent B-Raf inhibitor, with an IC50 of 24.79 nM. B-Raf IN 9 induces apoptosis and shows cell cycle arrest at G2/M phase. B-Raf IN 9 exhibits potent antitumor activity against human prostate cancer PC-3 cell line, with an IC50 of 7.83 µM[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> Raf
Target	B-Raf:24.97 ± 0. nM (IC50)
References	[1]. Thabit MG, et al. Design, synthesis and molecular modeling of phenyl dihydropyridazinone derivatives as B-Raf inhibitors with anticancer activity. Bioorg Chem. 2020 Oct;103:104148.

Molecular Formula	C₂₃H₂₀N₄OS
Molecular Weight	400.50

B-Raf IN 9

Use of B-Raf IN 9

Names

B-Raf IN 9 Biological Activity

Chemical & Physical Properties