Ms-PEG4-Ms
Modify Date: 2024-01-02 13:20:09
Ms-PEG4-Ms structure
|
Common Name | Ms-PEG4-Ms | ||
|---|---|---|---|---|
| CAS Number | 55400-73-2 | Molecular Weight | 350.40600 | |
| Density | 1.31g/cm3 | Boiling Point | 533.6ºC at 760 mmHg | |
| Molecular Formula | C10H22O9S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 276.5ºC | |
Use of Ms-PEG4-MsMs-PEG4-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 1,11-Bis(methanesulfonyloxy)-3,6,9-trioxandecane |
|---|---|
| Synonym | More Synonyms |
| Description | Ms-PEG4-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.31g/cm3 |
|---|---|
| Boiling Point | 533.6ºC at 760 mmHg |
| Molecular Formula | C10H22O9S2 |
| Molecular Weight | 350.40600 |
| Flash Point | 276.5ºC |
| Exact Mass | 350.07100 |
| PSA | 131.19000 |
| LogP | 1.15020 |
| Index of Refraction | 1.47 |
|
~96%
Ms-PEG4-Ms CAS#:55400-73-2 |
| Literature: Bakleh; Sol; Estieu-Gionnet; Granet; Deleris; Krausz Tetrahedron, 2009 , vol. 65, # 36 p. 7385 - 7392 |
|
~24%
Ms-PEG4-Ms CAS#:55400-73-2 |
| Literature: Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503 |
|
~%
Ms-PEG4-Ms CAS#:55400-73-2 |
| Literature: Jalisatgi, Satish S.; Kulkarni, Vikas S.; Tang, Betty; Houston, Zachary H.; Lee, Mark W.; Hawthorne, M. Frederick Journal of the American Chemical Society, 2011 , vol. 133, # 32 p. 12382 - 12385 |
| Precursor 2 | |
|---|---|
| DownStream 10 | |
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