Bay H 2049

Modify Date: 2024-01-09 16:33:41

Bay H 2049 structure	Common Name	Bay H 2049
	CAS Number	67199-66-0	Molecular Weight	249.27
	Density	1.46g/cm3	Boiling Point	524ºC at 760 mmHg
	Molecular Formula	C₁₅H₁₁N₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	270.7ºC

Use of Bay H 2049

Batracylin (NSC320846) is a potent DNA Topoisomerases I and DNA Topoisomerases II inhibitor. Batracylin shows cytotoxicity and antiproliferative activity. Batracylin induces DNA breaks[1].

Name	8-amino-10H-isoindolo[1,2-b]quinazolin-12-one
Synonym	More Synonyms

Description	Batracylin (NSC320846) is a potent DNA Topoisomerases I and DNA Topoisomerases II inhibitor. Batracylin shows cytotoxicity and antiproliferative activity. Batracylin induces DNA breaks[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
References	[1]. Rao VA, et al. Batracylin (NSC 320846), a dual inhibitor of DNA topoisomerases I and II induces histone gamma-H2AX as a biomarker of DNA damage. Cancer Res. 2007 Oct 15;67(20):9971-9.

Density	1.46g/cm3
Boiling Point	524ºC at 760 mmHg
Molecular Formula	C₁₅H₁₁N₃O
Molecular Weight	249.27
Flash Point	270.7ºC
Exact Mass	249.09000
PSA	58.69000
LogP	2.27120
Index of Refraction	1.781

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NR3900000

CHEMICAL NAME :: Isoindolo(1,2-b)quinazolin-12(10H)-one, 8-amino-

CAS REGISTRY NUMBER :: 67199-66-0

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C15-H11-N3-O

MOLECULAR WEIGHT :: 249.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Rodent - rat Liver

DOSE/DURATION :: 1 umol/L

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 126,39,1994

Precursor 6
CAS#:511530-08-8 N-[2-(phthalimi... CAS#:104-04-1 4-Nitroacetanilide CAS#:85-44-9 Phthalic anhydride CAS#:95182-27-7 Carbamic acid, ...
CAS#:106-50-3 p-Phenylenediamine CAS#:140-50-1 Acetamide,N,N'-...
DownStream 0

batracyclin

Batracylin

Daniquidona [INN-Spanish]

8-aminoisoindolo<1,2-b>quinazolin-12(10H)-one

Isoindolo(1,2-b)quinazolin-12(10H)-one,8-amino

Daniquidonum [INN-Latin]

Daniquidone

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Bay H 2049
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Purity: 99.47%
Delivery: 10 Day
Contact: Yang
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Bay H 2049
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Contact: Ms Wang
Email: enquiry@dycnchem.com

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