Hydroxy-PEG7-CH2-Boc

Modify Date: 2024-01-10 11:20:00

Hydroxy-PEG7-CH2-Boc Structure
Hydroxy-PEG7-CH2-Boc structure
Common Name Hydroxy-PEG7-CH2-Boc
CAS Number 2378049-28-4 Molecular Weight 440.53
Density N/A Boiling Point N/A
Molecular Formula C20H40O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hydroxy-PEG7-CH2-Boc


Hydroxy-PEG7-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Hydroxy-PEG7-CH2-Boc

 Hydroxy-PEG7-CH2-Boc Biological Activity

Description Hydroxy-PEG7-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C20H40O10
Molecular Weight 440.53