NH2-C6-NH-Boc

Modify Date: 2024-01-09 17:08:16

NH2-C6-NH-Boc Structure
NH2-C6-NH-Boc structure
Common Name NH2-C6-NH-Boc
CAS Number 51857-17-1 Molecular Weight 216.320
Density 1.0±0.1 g/cm3 Boiling Point 325.3±25.0 °C at 760 mmHg
Molecular Formula C11H24N2O2 Melting Point N/A
MSDS Chinese USA Flash Point 150.5±23.2 °C
Symbol GHS05
GHS05
Signal Word Danger

 Use of NH2-C6-NH-Boc


NH2-C6-NH-Boc is a PROTAC linker which refers to the alkyl/ether composition. NH2-C6-NH-Boc can be used in the synthesis the Mcl-1 inhibitor based on PROTAC[1].

 Names

Name N-tert-Butoxycarbonyl-1,6-hexanediamine
Synonym More Synonyms

 NH2-C6-NH-Boc Biological Activity

Description NH2-C6-NH-Boc is a PROTAC linker which refers to the alkyl/ether composition. NH2-C6-NH-Boc can be used in the synthesis the Mcl-1 inhibitor based on PROTAC[1].
Related Catalog
References

[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Aug 21.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 325.3±25.0 °C at 760 mmHg
Molecular Formula C11H24N2O2
Molecular Weight 216.320
Flash Point 150.5±23.2 °C
Exact Mass 216.183777
PSA 64.35000
LogP 1.82
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.460

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;
Risk Phrases R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 2735 8/PG 2
WGK Germany 3
Packaging Group III
Hazard Class 8
HS Code 2924199090

 Synthetic Route

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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 Synonyms

N-(tert-Butoxycarbonyl)-1,6-diaminohexane
N-Boc-1,6-hexanediamine
tert-Butyl (6-aminohexyl)carbamate
N-Boc-1,6-Diaminohexane
N-(6-Aminohexyl)carbamic Acid tert-Butyl Ester
tert-butyl N-(6-aminohexyl)carbamate
Carbamic acid, N-(6-aminohexyl)-, 1,1-dimethylethyl ester
MFCD00671489
2-Methyl-2-propanyl (6-aminohexyl)carbamate
N-(tert-Butoxycarbonyl)-1,6-hexanediamine
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