NH2-C4-NH-Boc structure
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Common Name | NH2-C4-NH-Boc | ||
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CAS Number | 68076-36-8 | Molecular Weight | 188.267 | |
Density | 1.0±0.1 g/cm3 | Boiling Point | 292.9±23.0 °C at 760 mmHg | |
Molecular Formula | C9H20N2O2 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 130.9±22.6 °C | |
Symbol |
GHS05 |
Signal Word | Danger |
Use of NH2-C4-NH-BocNH2-C4-NH-Boc (compound 15) is a PROTAC linker, which refers to the Alkyl/ether composition. NH2-C4-NH-Boc can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Name | tert-Butyl N-(4-aminobutyl)carbamate |
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Synonym | More Synonyms |
Description | NH2-C4-NH-Boc (compound 15) is a PROTAC linker, which refers to the Alkyl/ether composition. NH2-C4-NH-Boc can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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Related Catalog | |
Target |
Alkyl/ether |
References |
Density | 1.0±0.1 g/cm3 |
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Boiling Point | 292.9±23.0 °C at 760 mmHg |
Molecular Formula | C9H20N2O2 |
Molecular Weight | 188.267 |
Flash Point | 130.9±22.6 °C |
Exact Mass | 188.152481 |
PSA | 64.35000 |
LogP | 1.06 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.457 |
Symbol |
GHS05 |
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Signal Word | Danger |
Hazard Statements | H314 |
Precautionary Statements | P280-P305 + P351 + P338-P310 |
Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | C |
Risk Phrases | R34 |
Safety Phrases | S26-S36/37/39-S45 |
RIDADR | UN 2735 8/PG 3 |
WGK Germany | 3 |
Hazard Class | 8.0 |
HS Code | 2924199090 |
Precursor 9 | |
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DownStream 9 | |
HS Code | 2924199090 |
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Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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2-Methyl-2-propanyl (4-aminobutyl)carbamate |
BOC-NH(CH2)4NH2 HCL |
tert-butyl 4-aminobutylcarbamate |
Carbamic acid, N-(4-aminobutyl)-, 1,1-dimethylethyl ester |
(4-amino-butyl)-carbamic acid tert-butyl ester |
N-(1,1-dimethylethoxycarbonyl)-1,4-butanediamine |
BOC-DIAMINOBUTANE HCL |
N-Boc-1,4-butanediamine |
N-Boc-1,4-butandiamine |
N-T-BOC-BUTANDIAMINE HCL |
(4-aminobutyl)carbamic acid 1,1-dimethylethyl ester |
BUTTPARK 121 6-09 |
RARECHEM AR PA 0023 |
tert-ButylN-(4-aminobutyl)carbamate |
4-(t-butoxycarbonylamino)butylamine |
N-BOC-1,4-DIAMINOBUTANE |
AURORA KA-4397 |
N-(tert-butoxycarbonyl)-1,4-diamino-butane |
BOC-DAB HCL |
N-tert-Butoxycarbonyl-1,4-butanediamine |
MFCD02090802 |
tert-butyl 4-amino butylcarbamate |