LRRK2/NUAK1/TYK2-IN-1

Modify Date: 2024-04-05 21:30:20

LRRK2/NUAK1/TYK2-IN-1 Structure
LRRK2/NUAK1/TYK2-IN-1 structure
Common Name LRRK2/NUAK1/TYK2-IN-1
CAS Number 2629192-96-5 Molecular Weight 392.34
Density N/A Boiling Point N/A
Molecular Formula C20H11F3N6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LRRK2/NUAK1/TYK2-IN-1


LRRK2/NUAK1/TYK2-IN-1 (conpound 226) shows inhibitory activity toward LRRK2 (Wt), LRRK2 (G2019), TYK2 and NUAK1, with IC50 values lower than 10 nM. LRRK2/NUAK1/TYK2-IN-1 can be used for autoimmune disease research[1].

 Names

Name LRRK2/NUAK1/TYK2-IN-1

 LRRK2/NUAK1/TYK2-IN-1 Biological Activity

Description LRRK2/NUAK1/TYK2-IN-1 (conpound 226) shows inhibitory activity toward LRRK2 (Wt), LRRK2 (G2019), TYK2 and NUAK1, with IC50 values lower than 10 nM. LRRK2/NUAK1/TYK2-IN-1 can be used for autoimmune disease research[1].
Related Catalog
Target

Tyk2

NUAK1

References

[1]. Roland Koestler, et al. 1,4-dihydrobenzo[d]pyrazolo[3,4-f][1,3]diazepine derivatives and related compounds as lrrk2, nuak1 and/or tyk2 kinase modulators for the treatment of e.g. autoimmune disease. Patent WO2021048618A1.

 Chemical & Physical Properties

Molecular Formula C20H11F3N6
Molecular Weight 392.34