BC-21
Modify Date: 2024-01-10 20:19:55
BC-21 structure
|
Common Name | BC-21 | ||
|---|---|---|---|---|
| CAS Number | 691005-38-6 | Molecular Weight | 680.659 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C32H36Cl2Cu2N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BC-21BC-21 (NSC 109268) is a novel small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 6.55 uM; decreases the viability of β-catenin overexpressing HCT116 colon cancer cells that harbor the β-catenin mutation, and inhibits the clonogenic activity of these cells; inhibits Wnt/β-catenin signaling and down-regulates c-Myc and cyclin D1 expression in HCT116 cells. |
| Name | BC-21 |
|---|
| Description | BC-21 (NSC 109268) is a novel small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 6.55 uM; decreases the viability of β-catenin overexpressing HCT116 colon cancer cells that harbor the β-catenin mutation, and inhibits the clonogenic activity of these cells; inhibits Wnt/β-catenin signaling and down-regulates c-Myc and cyclin D1 expression in HCT116 cells. |
|---|---|
| References | References 1. Tian W, et al. Biochemistry. 2012 Jan 17;51(2):724-31. 2. Tian W, et al. J Biomol Screen. 2012 Apr;17(4):530-4. 3. Jain D, et al. Cancer Chemother Pharmacol. 2010 Oct;66(5):945-52. View Related Products by Target Beta-catenin |
| Molecular Formula | C32H36Cl2Cu2N2O2 |
|---|---|
| Molecular Weight | 680.659 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: BC-21
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: BC-21
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: BC-21
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
Get all suppliers and price by the below link: