BC-23

Modify Date: 2024-01-12 21:49:44

BC-23 Structure
BC-23 structure
Common Name BC-23
CAS Number 6298-15-3 Molecular Weight 439.87
Density 1.56g/cm3 Boiling Point 615.9ºC at 760mmHg
Molecular Formula C21H14ClN3O4S Melting Point N/A
MSDS N/A Flash Point 326.3ºC

 Use of BC-23


BC-23 (NSC 45382) is a proteasome inhibitor. BC-23 exhibits good inhibition of CT-L activity of the proteasome and is selective for malignant over normal cells[1][2].

 Names

Name 3--2-chlor-1.4-naphthochinon

 Chemical & Physical Properties

Density 1.56g/cm3
Boiling Point 615.9ºC at 760mmHg
Molecular Formula C21H14ClN3O4S
Molecular Weight 439.87
Flash Point 326.3ºC
Exact Mass 439.03900
PSA 113.61000
LogP 5.05070
Index of Refraction 1.721

 Synthetic Route

~53%

BC-23 Structure

BC-23

CAS#:6298-15-3

Literature: Lawrence, Harshani R.; Kazi, Aslamuzzaman; Luo, Yunting; Kendig, Robert; Ge, Yiyu; Jain, Sanjula; Daniel, Kenyon; Santiago, Daniel; Guida, Wayne C.; Sebti, Said M. Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 15 p. 5576 - 5592

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BC-23 Structure

BC-23

CAS#:6298-15-3

Literature: Calandra; Adams Journal of the American Chemical Society, 1950 , vol. 72, p. 4804
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